Kappa opioid antagonist effects of the novel kappa antagonist 5′-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys

Keyphrases

• Rhesus Monkey 100%
• Antagonist Activity 100%
• Kappa Opioid 100%
• Schedule-controlled Behavior 100%
• Kappa Antagonist 100%
• Morphine 60%
• U50,488 60%
• SNC80 60%
• Opioid Receptors 40%
• Receptor-mediated 40%
• Selective Antagonist 40%
• Kappa Receptor 40%
• Long Duration of Action 40%
• Decreasing Effect 40%
• Slow Onset 40%
• Monkey 20%
• High Dose 20%
• Antagonism 20%
• Opioid Antagonist 20%
• Response Rate 20%
• Nor-binaltorphimine (nor-BNI) 20%
• Mu Agonist 20%
• Kappa Agonist 20%
• Fixed Ratio 20%
• Time Selectivity 20%
• Delta Receptor 20%
• μ Receptor 20%
• Experimental Tools 20%
• Food Reinforcement 20%
• Schedule-controlled Responding 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Rhesus Monkey 100%
• Kappa Antagonists 100%
• 3,4 Dichloro N Methyl N [2 (1 Pyrrolidinyl)cyclohexyl]benzeneacetamide 60%
• Morphine 60%
• Opiate Receptor 40%
• Kappa Opiate Receptor 40%
• Haplorhini 20%
• Norbinaltorphimine 20%
• Receptor 20%
• Mu Opiate Receptor Agonist 20%
• Kappa Opiate Receptor Agonist 20%
• Delta Opiate Receptor Agonist 20%
• Delta Opiate Receptor 20%
• μ-Opioid Receptor 20%
• Narcotic Antagonist 20%