Prognostic usefulness of some parameters in dogs with canine parvovirus

Idil Bastan, Arif Kurtdede, Doǧukan Özen

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


The purpose of this study was to evaluate the prognostic usefulness of some parameters in dogs with canine parvovirus (CPV). Fifty-nine animals which consist of 39 ill and 20 healthy puppies were used in the study. All puppies were underwent a complete physical examination and laboratory variables (CBC, serum routine biochemistry profile, cTn-I, TNF-α) on their first admission to clinic and on following every day before treatment until discharge or death. Despite aggressive treatment with available therapy, 14 of 39 dogs died. Non-survivor dogs had significantly lower leukocyte, lymphocyte, monocyte and granulocyte counts but had significantly higher serum urea and creatinine concentrations than those of survivor dogs at presentation (p<0.05). Serum cTn-I concentration level were positive in 11of 14 non-survival dogs and negative in all of the survival dogs. The relative risk of death for the dogs with TNF-α positive was 3,39 times (95% CI:1,53-7,52) higher than that of dogs with TNF-α negative. This study demonstrates that leukocyte, lymphocyte, granulocyte, monocyte counts, serum urea and creatinine concentrations, cTn-I and TNF-α levels are useful parameters for predicting the prognosis of dogs with CPV.

Original languageEnglish (US)
Pages (from-to)53-58
Number of pages6
JournalAnkara Universitesi Veteriner Fakultesi Dergisi
Issue number1
StatePublished - 2012
Externally publishedYes


  • Canine parvovirus
  • Prognosis
  • TNF-α
  • cTn-I


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