K103N mutation in antiretroviral therapy-naive african patients infected with HIV type 1

Omobosola Akinsete; Diane Hirigoyen; Charles Cartwright; Ron Schut; Rami Kantor; William K Henry

doi:10.1086/422519

K103N mutation in antiretroviral therapy-naive african patients infected with HIV type 1

Omobosola Akinsete, Diane Hirigoyen, Charles Cartwright, Ron Schut, Rami Kantor, William K Henry

Medicine - Infectious Disease and International Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Most of the information about genetic sequencing and drug susceptibility of human immunodeficiency virus type 1 (HIV-1) is derived from the study of HIV-1 subtype B. Worldwide, most people infected with HIV-1 are infected with non-subtype B viruses and live in developing countries. We report 3 cases of antiretroviral-naive African immigrants infected with HIV-1 strains possessing the K103N mutation in the reverse transcriptase gene, which confers high-level resistance to all nonnucleoside reverse transcriptase inhibitors.

Original language	English (US)
Pages (from-to)	575-578
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	39
Issue number	4
DOIs	https://doi.org/10.1086/422519
State	Published - Aug 15 2004

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1086/422519

Find It

Find It at U of M Libraries

Cite this

@article{e959fe6a7c9641008f896783f63263ae,

title = "K103N mutation in antiretroviral therapy-naive african patients infected with HIV type 1",

abstract = "Most of the information about genetic sequencing and drug susceptibility of human immunodeficiency virus type 1 (HIV-1) is derived from the study of HIV-1 subtype B. Worldwide, most people infected with HIV-1 are infected with non-subtype B viruses and live in developing countries. We report 3 cases of antiretroviral-naive African immigrants infected with HIV-1 strains possessing the K103N mutation in the reverse transcriptase gene, which confers high-level resistance to all nonnucleoside reverse transcriptase inhibitors.",

author = "Omobosola Akinsete and Diane Hirigoyen and Charles Cartwright and Ron Schut and Rami Kantor and Henry, {William K}",

year = "2004",

month = aug,

day = "15",

doi = "10.1086/422519",

language = "English (US)",

volume = "39",

pages = "575--578",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

number = "4",

}

TY - JOUR

T1 - K103N mutation in antiretroviral therapy-naive african patients infected with HIV type 1

AU - Akinsete, Omobosola

AU - Hirigoyen, Diane

AU - Cartwright, Charles

AU - Schut, Ron

AU - Kantor, Rami

AU - Henry, William K

PY - 2004/8/15

Y1 - 2004/8/15

N2 - Most of the information about genetic sequencing and drug susceptibility of human immunodeficiency virus type 1 (HIV-1) is derived from the study of HIV-1 subtype B. Worldwide, most people infected with HIV-1 are infected with non-subtype B viruses and live in developing countries. We report 3 cases of antiretroviral-naive African immigrants infected with HIV-1 strains possessing the K103N mutation in the reverse transcriptase gene, which confers high-level resistance to all nonnucleoside reverse transcriptase inhibitors.

AB - Most of the information about genetic sequencing and drug susceptibility of human immunodeficiency virus type 1 (HIV-1) is derived from the study of HIV-1 subtype B. Worldwide, most people infected with HIV-1 are infected with non-subtype B viruses and live in developing countries. We report 3 cases of antiretroviral-naive African immigrants infected with HIV-1 strains possessing the K103N mutation in the reverse transcriptase gene, which confers high-level resistance to all nonnucleoside reverse transcriptase inhibitors.

UR - http://www.scopus.com/inward/record.url?scp=4344696210&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4344696210&partnerID=8YFLogxK

U2 - 10.1086/422519

DO - 10.1086/422519

M3 - Article

C2 - 15356825

AN - SCOPUS:4344696210

SN - 1058-4838

VL - 39

SP - 575

EP - 578

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 4

ER -

K103N mutation in antiretroviral therapy-naive african patients infected with HIV type 1

Abstract

UN SDGs

Publisher link

Find It

Other files and links

Fingerprint

Cite this