K103N mutation in antiretroviral therapy-naive african patients infected with HIV type 1

Omobosola Akinsete, Diane Hirigoyen, Charles Cartwright, Ron Schut, Rami Kantor, William K Henry

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Most of the information about genetic sequencing and drug susceptibility of human immunodeficiency virus type 1 (HIV-1) is derived from the study of HIV-1 subtype B. Worldwide, most people infected with HIV-1 are infected with non-subtype B viruses and live in developing countries. We report 3 cases of antiretroviral-naive African immigrants infected with HIV-1 strains possessing the K103N mutation in the reverse transcriptase gene, which confers high-level resistance to all nonnucleoside reverse transcriptase inhibitors.

Original languageEnglish (US)
Pages (from-to)575-578
Number of pages4
JournalClinical Infectious Diseases
Volume39
Issue number4
DOIs
StatePublished - Aug 15 2004

Fingerprint Dive into the research topics of 'K103N mutation in antiretroviral therapy-naive african patients infected with HIV type 1'. Together they form a unique fingerprint.

Cite this