Abstract
Cell junctions between Novikoff hepatoma cells (N1S1-67) growing as small clumps or chains in suspension culture have been studied with ultrastructural, electrophysiological, and dye-injection techniques. Cells within clumps are commonly electrically coupled and can exchange dyes with a molecular weight of 332 to 500. Gap junctions and intermediate junctions are present, whereas true tight junctions and desmosomes are absent or very rare. This system should provide a useful model for studying the properties of "communicating" junctions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 717-719 |
| Number of pages | 3 |
| Journal | Science |
| Volume | 174 |
| Issue number | 4010 |
| DOIs | |
| State | Published - 1971 |
