Junctional epidermolysis bullosa in a calf

Gildenor X. Medeiros, Franklin Riet-Correa, Anibal G. Armién, Antônio F.M. Dantas, Glauco J.N. de Galiza, Sara V.D. Simões

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


A case of epidermolysis bullosa in a calf descendent from a Gir bull and a Gir crossbreed cow is reported. The calf presented with exungulation of all hooves, widespread erosions and crusts on the skin, and ulcers in the oral cavity. Histologically, the skin showed subepidermal separation with clefts occasionally filled with eosinophilic clear fluid, cellular debris, or neutrophils. Ultrastructurally, there was epidermal-dermal separation at the level of the lamina lucida, with the lamina densa attached to the papillary dermis. The hemidesmosomes were poorly defined and small. The clinical, histological, and ultrastructural findings are characteristic of junctional epidermolysis bullosa.

Original languageEnglish (US)
Pages (from-to)231-234
Number of pages4
JournalJournal of Veterinary Diagnostic Investigation
Issue number1
StatePublished - Jan 2012

Bibliographical note

Copyright 2012 Elsevier B.V., All rights reserved.


  • Basal membrane
  • cattle
  • epidermolysis bullosa
  • mechanobullous diseases
  • skin diseases


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