Issues about the fMRI of the human spinal cord

Federico Giove, Girolamo Garreffa, Giovanni Giulietti, Silvia Mangia, Claudio Colonnese, Bruno Maraviglia

Research output: Contribution to journalArticlepeer-review

67 Scopus citations


Noninvasive functional studies on human spinal cord by means of magnetic resonance imaging (MRI) are gaining attention because of the promising applications in the study of healthy and injured central nervous system. The findings obtained are generally consistent with the anatomic knowledge based on invasive methods, but the origin and specificity of functional contrast is still debated. In this paper, a review of current knowledge and major issues about functional MRI (fMRI) in the human spinal cord is presented, with emphasis on the main methodological and technical problems and on forthcoming applications as clinical tool.

Original languageEnglish (US)
Pages (from-to)1505-1516
Number of pages12
JournalMagnetic Resonance Imaging
Issue number10 SPEC. ISS.
StatePublished - Dec 2004


  • BOLD
  • Functional MRI
  • Human
  • SEEP
  • Spinal cord


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