Isotope effects as new proxies for organic pollutant transformation

Thomas B. Hofstetter, Jakov Bolotin, Sarah G. Pati, Marita Skarpeli-Liati, Stephanie Spahr, Reto S. Wijker

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Assessing the pathways and rates of organic pollutant transformation in the environment is a major challenge due to co-occurring transport and degradation processes. Measuring changes of stable isotope ratios (e.g.13C/12C2H/1H, 15N/14N) in individual organic compounds by compound-specific isotope analysis (CSIA) makes it possible to identify degradation pathways without the explicit need to quantify pollutant concentration dynamics. The so-called isotope fractionation observed in an organic pollutant is related to isotope effects of (bio)chemical reactions and enables one to characterize pollutant degradation even if multiple processes take place simultaneously. Here, we illustrate some principles of CSIA using benzotriazole, a frequently observed aquatic micropollutant, as example. We show subsequently how the combined C and N isotope fractionation analysis of nitroaromatic compounds reveals kinetics and mechanisms of reductive and oxidative reactions as well as their (bio)degradation pathways in the environment.

Original languageEnglish (US)
Pages (from-to)788-792
Number of pages5
Issue number11
StatePublished - Nov 1 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Schweizerische Chemische Gesellschaft.


  • Compound-specific isotope analysis
  • Degradation mechanism
  • Kinetic isotope effect
  • Pollutant transformation


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