Isotope assay of histamine release

Malcolm N Blumenthal, Beatrice Roitman, Gary Carlson, Lloyd Fish

Research output: Contribution to journalArticlepeer-review

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The single isotopic enzymatic histamine assay system has been adopted for the studying of the release of histamine from sensitized human leukocytes when challenged with the appropriate allergen. It is a simple, rapid, sensitive, and reproducible method based on the use of the enzyme histamine N-methyltransferase and the high specific activity of tritiated S adenosylmethionine.

Original languageEnglish (US)
Pages (from-to)312-317
Number of pages6
JournalBiochemical medicine
Issue number4
StatePublished - Dec 1974

Bibliographical note

Funding Information:
1 This study was supported by funds of the Department of Minnesota Medical School and the Allergy Research Fund. 312 Copyright @ 1974 by Academic Press, Inc. All rights of reproduction in any form reserved.

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