Isolation of a low molecular weight glycoprotein inhibitor of calcium phosphate precipitation from the extra-parotid saliva of macaque monkeys

T. E. VanDyke; M. J. Levine; M. C. Herzberg; S. A. Ellison; D. I. Hay

doi:10.1016/0003-9969(79)90054-2

Isolation of a low molecular weight glycoprotein inhibitor of calcium phosphate precipitation from the extra-parotid saliva of macaque monkeys

T. E. VanDyke, M. J. Levine, M. C. Herzberg, S. A. Ellison, D. I. Hay

Diagnostic and Biological Sciences

Research output: Contribution to journal › Article › peer-review

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Abstract

A low molecular weight (9600) glycoprotein was isolated from monkey (Macaca arctoides) extra-parotid saliva by gel filtration on Sephadex G-200 and Sephadex G-50. Criteria of purity included immunodiffusion, immunoelectrophoresis and polyacrylamide gel electrophoresis. The molecule contained 76 per cent protein, 23.4 per cent carbohydrate and 0.6 per cent phosphorus. The glycoprotein was a potent inhibitor of calcium phosphate precipitation.

Original language	English (US)
Pages (from-to)	85-89
Number of pages	5
Journal	Archives of Oral Biology
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/0003-9969(79)90054-2
State	Published - 1979

Bibliographical note

Funding Information:
AcknoMlc,dyerncnrs~ We would like to acknowledge the excellent technical assistance of Mr. John P. Shomers and Mr. Gary E. Sadowski. This study wa supported in part by the National Institute of Dental Research. NIH, Training Grant No. 5T32DE07034. Research Grants No. IR23DE04518. No. SPOlDE03841 and N0. 5507RRO5330.

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title = "Isolation of a low molecular weight glycoprotein inhibitor of calcium phosphate precipitation from the extra-parotid saliva of macaque monkeys",

abstract = "A low molecular weight (9600) glycoprotein was isolated from monkey (Macaca arctoides) extra-parotid saliva by gel filtration on Sephadex G-200 and Sephadex G-50. Criteria of purity included immunodiffusion, immunoelectrophoresis and polyacrylamide gel electrophoresis. The molecule contained 76 per cent protein, 23.4 per cent carbohydrate and 0.6 per cent phosphorus. The glycoprotein was a potent inhibitor of calcium phosphate precipitation.",

author = "VanDyke, {T. E.} and Levine, {M. J.} and Herzberg, {M. C.} and Ellison, {S. A.} and Hay, {D. I.}",

note = "Funding Information: AcknoMlc,dyerncnrs~ We would like to acknowledge the excellent technical assistance of Mr. John P. Shomers and Mr. Gary E. Sadowski. This study wa supported in part by the National Institute of Dental Research. NIH, Training Grant No. 5T32DE07034. Research Grants No. IR23DE04518. No. SPOlDE03841 and N0. 5507RRO5330.",

year = "1979",

doi = "10.1016/0003-9969(79)90054-2",

language = "English (US)",

volume = "24",

pages = "85--89",

journal = "Archives of Oral Biology",

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TY - JOUR

T1 - Isolation of a low molecular weight glycoprotein inhibitor of calcium phosphate precipitation from the extra-parotid saliva of macaque monkeys

AU - VanDyke, T. E.

AU - Levine, M. J.

AU - Herzberg, M. C.

AU - Ellison, S. A.

AU - Hay, D. I.

N1 - Funding Information: AcknoMlc,dyerncnrs~ We would like to acknowledge the excellent technical assistance of Mr. John P. Shomers and Mr. Gary E. Sadowski. This study wa supported in part by the National Institute of Dental Research. NIH, Training Grant No. 5T32DE07034. Research Grants No. IR23DE04518. No. SPOlDE03841 and N0. 5507RRO5330.

PY - 1979

Y1 - 1979

N2 - A low molecular weight (9600) glycoprotein was isolated from monkey (Macaca arctoides) extra-parotid saliva by gel filtration on Sephadex G-200 and Sephadex G-50. Criteria of purity included immunodiffusion, immunoelectrophoresis and polyacrylamide gel electrophoresis. The molecule contained 76 per cent protein, 23.4 per cent carbohydrate and 0.6 per cent phosphorus. The glycoprotein was a potent inhibitor of calcium phosphate precipitation.

AB - A low molecular weight (9600) glycoprotein was isolated from monkey (Macaca arctoides) extra-parotid saliva by gel filtration on Sephadex G-200 and Sephadex G-50. Criteria of purity included immunodiffusion, immunoelectrophoresis and polyacrylamide gel electrophoresis. The molecule contained 76 per cent protein, 23.4 per cent carbohydrate and 0.6 per cent phosphorus. The glycoprotein was a potent inhibitor of calcium phosphate precipitation.

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JO - Archives of Oral Biology

JF - Archives of Oral Biology

IS - 2

ER -

Isolation of a low molecular weight glycoprotein inhibitor of calcium phosphate precipitation from the extra-parotid saliva of macaque monkeys

Abstract

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