Isolation and cloning of plant disease resistance genes

Nevin Dale Young

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Understanding the molecular basis of disease-resistance genes has long been a goal of plant pathology. With the advent of gene cloning technology in the 1970s, this goal finally became realistic and in the intervening years several important host defense-related genes have been cloned and characterized. 1 - 4 Nevertheless, the goal of cloning actual resistance genes, as opposed to host response genes, has remained elusive. For the most part, this is because most, if not all, disease-resistance genes are defined genetically through segregation analysis and transmission genetics. By contrast, current gene cloning techniques depend upon some biochemical connection to the gene, generally through the protein or mRNA product to isolate the gene. This explains why so many host response genes-and so few plant disease-resistance genes-have been cloned to date.

Original languageEnglish (US)
Title of host publicationMolecular Methods in Plant Pathology
PublisherCRC Press
Number of pages14
ISBN (Electronic)9781351430227
ISBN (Print)0873718771
StatePublished - Jan 1 2017

Bibliographical note

Publisher Copyright:
© 1995 by CRC Press, Inc.


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