Isolation and characterization of an antiviral flavonoid from waldsteinia fragarioides

Mohamed Abou Karam, W. Thomas Shier

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The antiviral agent in a fraction from Waldsteinia fragarioides (Rosaceae) was purified using bioassay-guided fractionation of activity against herpes simplex type 1 virus. Structural eluciation by instrumental methods identified the active component to be the known flavonoid glycoside, isoquercitrin (3,3′,4′,5,7-pentahydroxyflavone-3β-O-glucoside), which had not previously been shown to possess antiviral activity.

Original languageEnglish (US)
Pages (from-to)1525-1527
Number of pages3
JournalJournal of Natural Products
Volume55
Issue number10
DOIs
StatePublished - Oct 1 1992

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