Isolated optic nerve sarcoidosis

Sandip Suresh, Gregory S. Kosmorsky, Michael S. Lee

Research output: Contribution to journalArticlepeer-review


Objective: To report three cases of sarcoidosis confined to the optic nerve. Methods: Chart review of clinical, laboratory, imaging, and optic nerve biopsy findings and a review of the literature. Results: All three cases presented with progressive visual loss and showed enhancement of the intraorbital optic nerve on magnetic resonance imaging. There was no evidence for systemic disease, including a negative workup for sarcoidosis or other infiltrative pathologies. Optic nerve biopsy in each case showed non-caseating granulomas consistent with sarcoidosis. Conclusions: Sarcoidosis confined to the optic nerve is a rare phenomenon but should still be considered in the differential diagnosis of progressive optic neuropathy, even in the absence of systemic disease.

Original languageEnglish (US)
Pages (from-to)179-183
Number of pages5
JournalSarcoidosis Vasculitis and Diffuse Lung Diseases
Issue number2
StatePublished - Jan 1 2017


  • Optic Nerve
  • Optic Neuritis
  • Optic Neuropathy
  • Sarcoidosis

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