iso-petromyroxols: Novel dihydroxylated tetrahydrofuran enantiomers from sea lamprey (Petromyzon marinus)

Ke Li, Cory O. Brant, Ugo Bussy, Harshita Pinnamaneni, Hinal Patel, Thomas R. Hoye, Weiming Li

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


An enantiomeric pair of new fatty acid-derived hydroxylated tetrahydrofurans, here named iso-petromyroxols, were isolated from sea lamprey larvae-conditioned water. The relative configuration of iso-petromyroxol was elucidated with 1D and 2D NMR spectroscopic analyses. The ratio of enantiomers (er) in the natural sample was measured by chiral-HPLC-MS/MS to be ca. 3:1 of (-)- to (+)-antipodes.

Original languageEnglish (US)
Pages (from-to)5215-5222
Number of pages8
Issue number3
StatePublished - Mar 1 2015

Bibliographical note

Publisher Copyright:
© 2015 by the authors; licensee MDPI.


  • Cyclostomata
  • Relative configuration
  • Stereoisomers


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