Abstract
Direct attack of the bis(μ-oxo)dicopper core on an arene appears feasible in tyrosinase and model complexes on the basis of studies of new [Cu(III)/2(μ-O)2]2+ compounds supported by bidentate imine/amine ligands. In the first demonstration of such reactivity for a bis(μ- uxo)dicopper core, decomposition of these intermediates caused hydroxylation of a pendant phenyl ring [Eq. (a) in a reaction analogous to that catalyzed by tyrosinase.
Original language | English (US) |
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Pages (from-to) | 1139-1142 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 38 |
Issue number | 8 |
DOIs | |
State | Published - Apr 19 1999 |
Keywords
- Copper
- Hydroxylations
- Monooxygenases
- Oxidases
- Tyrosinase