Is the 2,3-carbon-carbon bond of indole really inert to oxidative cleavage by Oxone?-Synthesis of isatoic anhydrides from indoles

Amber C. Nelson, Emily S. Kalinowski, Nikolas J. Czerniecki, Taylor L. Jacobson, Peter Grundt

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

A recent report has indicated that the oxidizing agent Oxone does not possess the ability to cleave the 2,3-carbon-carbon bond of indole. Work in our laboratory shows that this is not the case. Indole and a variety of aryl ring substituted derivatives readily react to form synthetically important isatoic anhydrides.

Original languageEnglish (US)
Pages (from-to)7455-7457
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume11
Issue number43
DOIs
StatePublished - Nov 21 2013

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