Despite the American Academy of Pediatrics' (AAP) strong endorsement for breastfeeding, most infants in the United States are fed some infant formula by the time they are 2 months old. The AAP Committee on Nutrition has strongly advocated iron fortification of infant formulas since 1969 as a way of reducing the prevalence of iron-deficiency anemia and its attendant sequelae during the first year. The 1976 statement titled 'Iron Supplementation for Infants' delineated the rationale for iron supplementation, proposed daily dosages of iron, and summarized potential sources of iron in the infant diet. In 1989, the AAP Committee on Nutrition published a statement that addressed the issue of iron-fortified infant formulas and concluded that there was no convincing contraindication to iron- supplemented formulas and that continued use of 'low-iron' formulas posed an unacceptable risk for iron deficiency during infancy. The current statement represents a scientific update and synthesis of the 1976 and 1989 statements with recommendations about the use of iron-fortified and low-iron formulas in term infants.