Hot couple: Propargyl azides were coupled with carboxylic acids by an iron-catalyzed dehydrogenative C-O bond formation (see scheme). This method enables propargylic C sp 3-H functionalization under mild reaction conditions and also may involve the application of the azido moiety as an assisting group in C-H activation.
|Original language||English (US)|
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|State||Published - Oct 22 2012|
- C-H activation
- C-O coupling
- carboxylic acids