Abstract
Hot couple: Propargyl azides were coupled with carboxylic acids by an iron-catalyzed dehydrogenative C-O bond formation (see scheme). This method enables propargylic C sp 3-H functionalization under mild reaction conditions and also may involve the application of the azido moiety as an assisting group in C-H activation.
Original language | English (US) |
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Pages (from-to) | 10823-10826 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 51 |
Issue number | 43 |
DOIs | |
State | Published - Oct 22 2012 |
Externally published | Yes |
Keywords
- C-H activation
- C-O coupling
- carboxylic acids
- cations
- iron