A direct oxidative approach to alkenyl aldehydes from allyl arenes via allyl sp3 C-H functionalization was disclosed. An inexpensive iron catalyst was employed to facilitate this transformation. The mechanistic studies indicate that the cleavage of the allyl sp3 C-H bond is involved in the rate-determining step.
Bibliographical noteFunding Information:
Financial support from Peking University, National Science Foundation of China (Nos. 20702002, 20872003 ) and National Basic Research Program of China (973 Program 2009CB825300) is greatly appreciated.