Iris and anterior chamber involvement in acute lymphoblastic leukemia

Sanjay V. Patel, David C. Herman, Peter M. Anderson, Naser J. Al-Zein, Helmut Buettner

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The authors describe a 6-year-old child, with a history of acute lymphoblastic leukemia, who presented with leukemic infiltration of the anterior segment of one eye mimicking anterior uveitis. After tissue diagnosis, administration of radiation therapy to the affected eye resulted in dramatic improvement of the condition. Involvement of the iris and anterior chamber is a recognized but unusual manifestation of leukemia. In the absence of systemic relapse, local radiation therapy without chemotherapy is highly effective, although the prognosis in these patients may be guarded.

Original languageEnglish (US)
Pages (from-to)653-656
Number of pages4
JournalJournal of pediatric hematology/oncology
Issue number8
StatePublished - Aug 2003


  • Acute lymphoblastic leukemia
  • Anterior chamber leukemia
  • Eye
  • Iris leukemia
  • Radiation therapy


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