The most widely used antipyretic and analgesic drug, acetaminophen, has the long standing problem of extremely poor tableting properties and has been considered as non-ionizable. Here we report the synthesis of the first ionized solid-state structure, acetaminophen HCl monohydrate, and demonstrate its excellent tableting properties.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Apr 7 2012|