(Diacetoxyiodo)benzene or iodine(III) catalyst, in situ generated from iodobenzene precatalyst with Oxone, promotes the cycloisomerization–amination sequence of N-propargyl carboxamides with bis(sulfonyl)imides under mild conditions, thereby leading to the direct formation of oxazoles bearing nitrogen functional groups. (Figure presented.).
Bibliographical noteFunding Information:
This work was partially supported by JSPS Grants-in-Aid for Scientific Research (C) (Grant No 15K07852), by the Society of Iodine Science and by the Takeda Science Foundation. V.V.Z. is also thankful to the National Science Foundation (CHE-1262479).