Involvement of the Akt/mTOR pathway on EGF-induced cell transformation

Keyphrases

• Cell Transformation 100%
• Epidermal Growth Factor 100%
• AKT/mammalian Target of Rapamycin 100%
• Mammalian Target of Rapamycin Pathway 100%
• Rapamycin 50%
• JB6 Cells 40%
• P13K 30%
• Mammalian Target of Rapamycin (mTOR) 30%
• Phosphorylation 30%
• AKT1 30%
• Dominant-negative mutant 30%
• Cell Proliferation 20%
• Protein Kinase 20%
• Epidermis 20%
• Activator protein-1 (AP-1) 20%
• Phosphoinositide 3-kinase (PI3K) 10%
• MTOR Inhibitor 10%
• Kinase Activation 10%
• Downstream Targets 10%
• Akt Activation 10%
• Downstream Effectors 10%
• Extracellular Regulated Protein Kinases 10%
• LY294002 10%
• Activation Treatment 10%

Biochemistry, Genetics and Molecular Biology

• Protein Kinase B 100%
• Cell Transformation 100%
• Epidermal Growth Factor 100%
• Mechanistic Target of Rapamycin 100%
• Protein Kinases 30%
• Cell Proliferation 20%
• AP-1 Transcription Factor 20%
• LY294002 10%
• Phosphoinositide 3-Kinase 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Epidermal Growth Factor 100%
• Mammalian Target of Rapamycin 100%
• Rapamycin 50%
• S6 Kinase 20%
• Transcription Factor AP 1 20%
• Mammalian Target of Rapamycin Inhibitor 10%
• Phosphatidylinositol 3 Kinase 10%
• 2 Morpholino 8 Phenylchromone 10%
• Protein Kinases 10%