Involvement of aeration in carbon source regulation of cephem antibiotic biosynthesis in Streptomyces clavuligerus

A. F. Brana, W. S. Hu, A. L. Demain

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The interference by glycerol and other carbon sources with production of cephem antibiotics by resting cells of Streptomyces clawligerus was found to be related to aeration conditions. When a low cell density or increased aeration was used, carbon sources did not have any effect on the rate of production.

Original languageEnglish (US)
Pages (from-to)791-794
Number of pages4
JournalBiotechnology Letters
Volume5
Issue number12
DOIs
StatePublished - Dec 1983

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