Opportunistic infections with fungal organisms have been well described in patients undergoing intensive chemotherapy and bone marrow transplantation. In two patients, invasive infections with the saprophyte Scopulariopsis developed either following intensive chemotherapy or bone marrow transplant. Fungal disease persisted in both patients despite resection of the primary focus and prolonged treatment with the usual antifungal agents, and contributed to the death of one patient.
Bibliographical noteFunding Information:
From the Departments of Pediatrics, Medicine, and Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota. This work was supported in part by the Coleman Leukemia Research Fund, National Institutes of Health Grants CA07306, CA21737, and T32 CA09445 and the Children’s Cancer Research Fund of the University of Minnesota. Dr. Neglia is the recipient of National Cancer Institute’s Clinical Investigator Award K08 CA01240. Requests for reprints should be addressed to Dr. David D. Hurd, University of Minnesota Hospital and Clinic, Box 155 UMHC, Harvard Street at East River Road, Minneapolis, Minnesota 55455. Manuscript submitted March 6, 1987, and accepted June 22, 1987.