In our review, we introduce an organizational scheme for membrane protein function. It is the relationship between structure, dynamics, arid, environment that endows the membrane and its constituents with-remarkable sensitivity and robustness. Our understanding begins with landmark like those presented in the following chapters. Membrane proteins are notoriously difficult to study, and so, the work presented here on the ADP/ATP carrier [Nury et al. (2)], rhodopsin [Palczewski (24)], and the cytochrome b6f complex [Cramer et al. (35)] represents incredible progress in this now blossoming field.
|Original language||English (US)|
|Number of pages||6|
|Journal||Annual Review of Biochemistry|
|State||Published - 2006|