Introduction and Overview of Stem Cells

Leslie W. Miller, Emerson C. Perin

Research output: Chapter in Book/Report/Conference proceedingChapter


One of the most exciting advances in medicine today has been the use of stem cell and gene therapy for repair in all forms of acute and chronic illness. Stem cells have been shown to be the primary mechanism for tissue repair everywhere in the body, and not limited to cardiovascular disease. Some have even opined that diseases like atherosclerosis represent a failure of stem cells. However, because cardiovascular disease has become the leading cause of death and morbidity in the world, it is the area that has seen the greatest evaluation by clinical trials of cell therapy in what is known as regenerative medicine. This introductory chapter is designed as a guide to understanding all the new sources and types of stem cells now in clinical trials, as well as the surface markers that help identify each type of cell.

Original languageEnglish (US)
Title of host publicationStem Cell and Gene Therapy for Cardiovascular Disease
PublisherElsevier Science, Ltd., Press
Number of pages9
ISBN (Electronic)9780128018637
ISBN (Print)9780128018880
StatePublished - Jan 1 2015
Externally publishedYes


  • Stem cell sources and types
  • Stem cells
  • Surface markers


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