Intraventricular cholecystokinin-octapeptide produces hypothermia in rats

John E. Morley; Allen S. Levine; Sandra Lindblad

doi:10.1016/0014-2999(81)90538-0

Intraventricular cholecystokinin-octapeptide produces hypothermia in rats

John E. Morley, Allen S. Levine, Sandra Lindblad

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Abstract

Intraventricular administration of cholecystokinin-octapeptide (CCK-8) in unanesthetized, unrestained rats produced hyopothermia in rats. The maximum fall in temperature after CCK-8 was -1.08±0.09°C. The temperature fall after CCK-8 was significantly suppressed from 15 to 60 min after intraventricular administration and returned to basal levels by 120 min.

Original language	English (US)
Pages (from-to)	249-251
Number of pages	3
Journal	European Journal of Pharmacology
Volume	74
Issue number	2-3
DOIs	https://doi.org/10.1016/0014-2999(81)90538-0
State	Published - Sep 11 1981

Keywords

Cholecystokinin
Thermoregulation

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10.1016/0014-2999(81)90538-0

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title = "Intraventricular cholecystokinin-octapeptide produces hypothermia in rats",

abstract = "Intraventricular administration of cholecystokinin-octapeptide (CCK-8) in unanesthetized, unrestained rats produced hyopothermia in rats. The maximum fall in temperature after CCK-8 was -1.08±0.09°C. The temperature fall after CCK-8 was significantly suppressed from 15 to 60 min after intraventricular administration and returned to basal levels by 120 min.",

keywords = "Cholecystokinin, Thermoregulation",

author = "Morley, {John E.} and Levine, {Allen S.} and Sandra Lindblad",

year = "1981",

month = sep,

day = "11",

doi = "10.1016/0014-2999(81)90538-0",

language = "English (US)",

volume = "74",

pages = "249--251",

journal = "European Journal of Pharmacology",

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TY - JOUR

T1 - Intraventricular cholecystokinin-octapeptide produces hypothermia in rats

AU - Morley, John E.

AU - Levine, Allen S.

AU - Lindblad, Sandra

PY - 1981/9/11

Y1 - 1981/9/11

N2 - Intraventricular administration of cholecystokinin-octapeptide (CCK-8) in unanesthetized, unrestained rats produced hyopothermia in rats. The maximum fall in temperature after CCK-8 was -1.08±0.09°C. The temperature fall after CCK-8 was significantly suppressed from 15 to 60 min after intraventricular administration and returned to basal levels by 120 min.

AB - Intraventricular administration of cholecystokinin-octapeptide (CCK-8) in unanesthetized, unrestained rats produced hyopothermia in rats. The maximum fall in temperature after CCK-8 was -1.08±0.09°C. The temperature fall after CCK-8 was significantly suppressed from 15 to 60 min after intraventricular administration and returned to basal levels by 120 min.

KW - Cholecystokinin

KW - Thermoregulation

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UR - http://www.scopus.com/inward/citedby.url?scp=0019355083&partnerID=8YFLogxK

U2 - 10.1016/0014-2999(81)90538-0

DO - 10.1016/0014-2999(81)90538-0

M3 - Article

C2 - 6276188

AN - SCOPUS:0019355083

VL - 74

SP - 249

EP - 251

JO - European Journal of Pharmacology

JF - European Journal of Pharmacology

SN - 0014-2999

IS - 2-3

ER -

Intraventricular cholecystokinin-octapeptide produces hypothermia in rats

Abstract

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