We gave verapamil intravenously to 16 patients who had multifocal atrial tachycardia - five patients were pretreated with 1 g of intravenous calcium gluconate five minutes before receiving verapamil and 11 patients were not. Verapamil proved effective and safe, slowing the heart rate in all but one patient (21% average decrease) and restoring sinus rhythm in eight. Although without calcium pretreatment verapamil therapy resulted in a 27% decrease in systolic blood pressure, with calcium pretreatment the systolic pressure decreased only 11%. Calcium pretreatment did not prevent the slowing effect of verapamil on heart rate.
|Original language||English (US)|
|Number of pages||18|
|Journal||Cardiology Board Review|
|State||Published - Jan 1 1988|