Keyphrases
Pharmacokinetics-pharmacodynamics (PK-PD)
100%
Allopregnanolone
100%
Status Epilepticus
100%
Early Treatment
100%
Intramuscular Administration
33%
Intracranial EEG (iEEG)
33%
Sedation
22%
Tolerability
11%
Plasma Concentration
11%
Dose-ranging
11%
Intravenous Infusion
11%
High Dose
11%
Ataxia
11%
Intravenous Administration
11%
Synaptic
11%
Healthy Dogs
11%
Blood Samples
11%
Adverse Events
11%
EC50
11%
Vital Signs
11%
Rapid Onset
11%
Emax
11%
Maximum Response
11%
Power Spectral Density
11%
Concentration-response
11%
Neurosteroids
11%
Sedation Assessment
11%
History of Epilepsy
11%
Absolute Power
11%
EEG Changes
11%
Extrasynaptic GABAA Receptors
11%
Injection Pain
11%
Onset of Effect
11%
PK-PD Model
11%
Intravenous Dose
11%
EEG Power Spectrum
11%
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacodynamics
100%
Brexanolone
100%
Epileptic State
100%
Pharmacokinetics
100%
Intramuscular Injection
33%
Tolerability
11%
Receptor
11%
Adverse Event
11%
Injection Site Pain
11%
PK/PD Models
11%
Bioavailability
11%
Ataxia
11%
Neurosteroid
11%
EC50
11%