Intravascular pseudolymphomatous angiosarcoma: A new finding potentially mistaken for intravascular lymphoma

Amrita Goyal-O'Leary, Whitney D Tope, Paari Murugan, Erick Jacobson-Dunlop, Daniel D. Miller

Research output: Contribution to journalArticlepeer-review


Pseudolymphomatous infiltrates associated with angiosarcoma are a rarely reported phenomenon. Recognition of this reactive process is critical to making an accurate diagnosis, both in diagnosing the angiosarcoma and in avoiding an incorrect diagnosis of lymphoma. Here, we present a novel histopathologic pattern, angiosarcoma with a prominently intravascular atypical lymphoid component, mimicking intravascular T-cell lymphoma. Interestingly, serial biopsies in this case revealed a progressive increase in lymphocyte density and intravascular component over time. Despite prior reports of improved progression-free survival and overall survival of patients with pseudolymphomatous angiosarcoma, this patient showed rapid disease progression.

Original languageEnglish (US)
Pages (from-to)1080-1084
Number of pages5
JournalJournal of cutaneous pathology
Issue number8
Early online dateApr 25 2021
StatePublished - Aug 2021

Bibliographical note

Publisher Copyright:
© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd


  • angiosarcoma
  • intravascular lymphoma
  • lymphomatous angiosarcoma
  • pseudolymphomatous angiosarcoma

PubMed: MeSH publication types

  • Case Reports


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