Intraoperative magnetic resonance imaging assessment of non-functioning pituitary adenomas during transsphenoidal surgery

Kunal S. Patel, Yong Yao, Renzhi Wang, Bob S. Carter, Clark C. Chen

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Purpose: To review the utility of intraoperative imaging in facilitating maximal resection of non-functioning pituitary adenomas (NFAs). Methods: We performed an exhaustive MEDLINE search, which yielded 5598 articles. Upon careful review of these studies, 31 were pertinent to the issue of interest. Results: Nine studies examined whether intraoperative MRI (iMRI) findings correlated with the presence of residual tumor on MRI taken 3 months after surgical resection. All studies using iMRI of >0.15T showed a ≥90 % concordance between iMRI and 3-month post-operative MRI findings. 24 studies (22 iMRI and 2 intraoperative CT) examined whether intraoperative imaging improved the surgeon’s ability to achieve a more complete resection. The resections were carried out under microscopic magnification in 17 studies and under endoscopic visualization in 7 studies. All studies support the value of intraoperative imaging in this regard, with improved resection in 15–83 % of patients. Two studies examined whether iMRI (≥0.3T) improved visualization of residual NFA when compared to endoscopic visualization. Both studies demonstrated the value of iMRI in this regard, particularly when the tumor is located lateral of the sella, in the cavernous sinus, and in the suprasellar space. Conclusion: The currently available literature supports the utility of intraoperative imaging in facilitating increased NFA resection, without compromising safety.

Original languageEnglish (US)
Pages (from-to)222-231
Number of pages10
JournalPituitary
Volume19
Issue number2
DOIs
StatePublished - Apr 1 2016

Fingerprint

Pituitary Neoplasms
Magnetic Resonance Imaging
Cavernous Sinus
Residual Neoplasm
MEDLINE
Safety
Neoplasms

Keywords

  • Computed tomography
  • Endoscopy
  • Intraoperative
  • Magnetic resonance imaging
  • Non-functioning pituitary adenomas

Cite this

Intraoperative magnetic resonance imaging assessment of non-functioning pituitary adenomas during transsphenoidal surgery. / Patel, Kunal S.; Yao, Yong; Wang, Renzhi; Carter, Bob S.; Chen, Clark C.

In: Pituitary, Vol. 19, No. 2, 01.04.2016, p. 222-231.

Research output: Contribution to journalReview article

Patel, Kunal S. ; Yao, Yong ; Wang, Renzhi ; Carter, Bob S. ; Chen, Clark C. / Intraoperative magnetic resonance imaging assessment of non-functioning pituitary adenomas during transsphenoidal surgery. In: Pituitary. 2016 ; Vol. 19, No. 2. pp. 222-231.
@article{356a5f503b844bf481ccf72482c8989e,
title = "Intraoperative magnetic resonance imaging assessment of non-functioning pituitary adenomas during transsphenoidal surgery",
abstract = "Purpose: To review the utility of intraoperative imaging in facilitating maximal resection of non-functioning pituitary adenomas (NFAs). Methods: We performed an exhaustive MEDLINE search, which yielded 5598 articles. Upon careful review of these studies, 31 were pertinent to the issue of interest. Results: Nine studies examined whether intraoperative MRI (iMRI) findings correlated with the presence of residual tumor on MRI taken 3 months after surgical resection. All studies using iMRI of >0.15T showed a ≥90 {\%} concordance between iMRI and 3-month post-operative MRI findings. 24 studies (22 iMRI and 2 intraoperative CT) examined whether intraoperative imaging improved the surgeon’s ability to achieve a more complete resection. The resections were carried out under microscopic magnification in 17 studies and under endoscopic visualization in 7 studies. All studies support the value of intraoperative imaging in this regard, with improved resection in 15–83 {\%} of patients. Two studies examined whether iMRI (≥0.3T) improved visualization of residual NFA when compared to endoscopic visualization. Both studies demonstrated the value of iMRI in this regard, particularly when the tumor is located lateral of the sella, in the cavernous sinus, and in the suprasellar space. Conclusion: The currently available literature supports the utility of intraoperative imaging in facilitating increased NFA resection, without compromising safety.",
keywords = "Computed tomography, Endoscopy, Intraoperative, Magnetic resonance imaging, Non-functioning pituitary adenomas",
author = "Patel, {Kunal S.} and Yong Yao and Renzhi Wang and Carter, {Bob S.} and Chen, {Clark C.}",
year = "2016",
month = "4",
day = "1",
doi = "10.1007/s11102-015-0679-9",
language = "English (US)",
volume = "19",
pages = "222--231",
journal = "Pituitary",
issn = "1386-341X",
publisher = "Kluwer Academic Publishers",
number = "2",

}

TY - JOUR

T1 - Intraoperative magnetic resonance imaging assessment of non-functioning pituitary adenomas during transsphenoidal surgery

AU - Patel, Kunal S.

AU - Yao, Yong

AU - Wang, Renzhi

AU - Carter, Bob S.

AU - Chen, Clark C.

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Purpose: To review the utility of intraoperative imaging in facilitating maximal resection of non-functioning pituitary adenomas (NFAs). Methods: We performed an exhaustive MEDLINE search, which yielded 5598 articles. Upon careful review of these studies, 31 were pertinent to the issue of interest. Results: Nine studies examined whether intraoperative MRI (iMRI) findings correlated with the presence of residual tumor on MRI taken 3 months after surgical resection. All studies using iMRI of >0.15T showed a ≥90 % concordance between iMRI and 3-month post-operative MRI findings. 24 studies (22 iMRI and 2 intraoperative CT) examined whether intraoperative imaging improved the surgeon’s ability to achieve a more complete resection. The resections were carried out under microscopic magnification in 17 studies and under endoscopic visualization in 7 studies. All studies support the value of intraoperative imaging in this regard, with improved resection in 15–83 % of patients. Two studies examined whether iMRI (≥0.3T) improved visualization of residual NFA when compared to endoscopic visualization. Both studies demonstrated the value of iMRI in this regard, particularly when the tumor is located lateral of the sella, in the cavernous sinus, and in the suprasellar space. Conclusion: The currently available literature supports the utility of intraoperative imaging in facilitating increased NFA resection, without compromising safety.

AB - Purpose: To review the utility of intraoperative imaging in facilitating maximal resection of non-functioning pituitary adenomas (NFAs). Methods: We performed an exhaustive MEDLINE search, which yielded 5598 articles. Upon careful review of these studies, 31 were pertinent to the issue of interest. Results: Nine studies examined whether intraoperative MRI (iMRI) findings correlated with the presence of residual tumor on MRI taken 3 months after surgical resection. All studies using iMRI of >0.15T showed a ≥90 % concordance between iMRI and 3-month post-operative MRI findings. 24 studies (22 iMRI and 2 intraoperative CT) examined whether intraoperative imaging improved the surgeon’s ability to achieve a more complete resection. The resections were carried out under microscopic magnification in 17 studies and under endoscopic visualization in 7 studies. All studies support the value of intraoperative imaging in this regard, with improved resection in 15–83 % of patients. Two studies examined whether iMRI (≥0.3T) improved visualization of residual NFA when compared to endoscopic visualization. Both studies demonstrated the value of iMRI in this regard, particularly when the tumor is located lateral of the sella, in the cavernous sinus, and in the suprasellar space. Conclusion: The currently available literature supports the utility of intraoperative imaging in facilitating increased NFA resection, without compromising safety.

KW - Computed tomography

KW - Endoscopy

KW - Intraoperative

KW - Magnetic resonance imaging

KW - Non-functioning pituitary adenomas

UR - http://www.scopus.com/inward/record.url?scp=84940532451&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940532451&partnerID=8YFLogxK

U2 - 10.1007/s11102-015-0679-9

DO - 10.1007/s11102-015-0679-9

M3 - Review article

VL - 19

SP - 222

EP - 231

JO - Pituitary

JF - Pituitary

SN - 1386-341X

IS - 2

ER -