Intramuscular and intravenous levetiracetam in humans: Safety and pharmacokinetics

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10 Scopus citations

Abstract

A study in dogs demonstrated that the commercially available formulation of IV levetiracetam (LEV) could be given safely IM and was quickly and completely absorbed. In this crossover study, 5 women and 5 men were given IM and IV LEV. This study demonstrates that administration of 5. ml (500. mg) IM LEV is well tolerated and its bioavailability is equivalent to an IV injection.

Original languageEnglish (US)
Pages (from-to)289-292
Number of pages4
JournalEpilepsy Research
Volume91
Issue number2-3
DOIs
StatePublished - Oct 2010

Bibliographical note

Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.

Keywords

  • Half-life
  • Intramuscular
  • Intravenous
  • Levetiracetam
  • Pharmacokinetics

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