Interweaving the strands: β-catenin, an HIV Co-receptor, and schwann cell tumors

David Largaespada; Nancy Ratner

doi:10.1016/j.ccr.2013.03.001

Interweaving the strands: β-catenin, an HIV Co-receptor, and schwann cell tumors

David Largaespada
, Nancy Ratner

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

Abstract

WNT/β-catenin signaling is critical to the development of many cancer types. A paper by Mo and colleagues in a recent issue of Cell shows that autocrine CXCL12/CXCR4 chemokine signaling activates β-catenin signaling in a rare peripheral nerve sarcoma. Together with the availability of small molecules targeting CXCR4, this finding suggests new avenues for cancer therapy.

Original language	English (US)
Pages (from-to)	269-271
Number of pages	3
Journal	Cancer Cell
Volume	23
Issue number	3
DOIs	https://doi.org/10.1016/j.ccr.2013.03.001
State	Published - Mar 18 2013

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10.1016/j.ccr.2013.03.001

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title = "Interweaving the strands: β-catenin, an HIV Co-receptor, and schwann cell tumors",

abstract = "WNT/β-catenin signaling is critical to the development of many cancer types. A paper by Mo and colleagues in a recent issue of Cell shows that autocrine CXCL12/CXCR4 chemokine signaling activates β-catenin signaling in a rare peripheral nerve sarcoma. Together with the availability of small molecules targeting CXCR4, this finding suggests new avenues for cancer therapy.",

author = "David Largaespada and Nancy Ratner",

year = "2013",

month = mar,

day = "18",

doi = "10.1016/j.ccr.2013.03.001",

language = "English (US)",

volume = "23",

pages = "269--271",

journal = "Cancer Cell",

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number = "3",

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T1 - Interweaving the strands

T2 - β-catenin, an HIV Co-receptor, and schwann cell tumors

AU - Largaespada, David

AU - Ratner, Nancy

PY - 2013/3/18

Y1 - 2013/3/18

N2 - WNT/β-catenin signaling is critical to the development of many cancer types. A paper by Mo and colleagues in a recent issue of Cell shows that autocrine CXCL12/CXCR4 chemokine signaling activates β-catenin signaling in a rare peripheral nerve sarcoma. Together with the availability of small molecules targeting CXCR4, this finding suggests new avenues for cancer therapy.

AB - WNT/β-catenin signaling is critical to the development of many cancer types. A paper by Mo and colleagues in a recent issue of Cell shows that autocrine CXCL12/CXCR4 chemokine signaling activates β-catenin signaling in a rare peripheral nerve sarcoma. Together with the availability of small molecules targeting CXCR4, this finding suggests new avenues for cancer therapy.

UR - https://www.scopus.com/pages/publications/84876446664

UR - https://www.scopus.com/pages/publications/84876446664#tab=citedBy

U2 - 10.1016/j.ccr.2013.03.001

DO - 10.1016/j.ccr.2013.03.001

M3 - Short survey

C2 - 23518344

AN - SCOPUS:84876446664

SN - 1535-6108

VL - 23

SP - 269

EP - 271

JO - Cancer Cell

JF - Cancer Cell

IS - 3

ER -

Interweaving the strands: β-catenin, an HIV Co-receptor, and schwann cell tumors

Abstract

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