Abstract
Chronic diseases are associated with considerable morbidity and mortality. Therefore, new therapeutic strategies are warranted. Here, we provide a brief review outlining the rationale and feasibility for the generation of intraspecies and interspecies chimeras, which one day may serve as a platform for organ transplantation. These strategies are further associated with consideration of scientific and ethical issues.
Original language | English (US) |
---|---|
Pages (from-to) | 1838-1844 |
Number of pages | 7 |
Journal | Experimental Biology and Medicine |
Volume | 246 |
Issue number | 16 |
Early online date | Jun 24 2021 |
DOIs | |
State | Published - Aug 2021 |
Bibliographical note
Publisher Copyright:© 2021 by the Society for Experimental Biology and Medicine.
Keywords
- Chimera
- ETV2
- MYF5
- MYF6
- MYOD
- hiPSCs
- somatic cell nuclear transfer