Chronic diseases are associated with considerable morbidity and mortality. Therefore, new therapeutic strategies are warranted. Here, we provide a brief review outlining the rationale and feasibility for the generation of intraspecies and interspecies chimeras, which one day may serve as a platform for organ transplantation. These strategies are further associated with consideration of scientific and ethical issues.
|Original language||English (US)|
|Number of pages||7|
|Journal||Experimental Biology and Medicine|
|Early online date||Jun 24 2021|
|State||Published - Aug 2021|
Bibliographical noteFunding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This work was supported by the National Institutes of Health [HL144582] and the Department of Defense [grant numbers W81XWH2020047, W81XWH2020048 and W81WH1910610].
© 2021 by the Society for Experimental Biology and Medicine.
- somatic cell nuclear transfer