Intermolecular hydroamination of 1,3-dienes catalyzed by bis(phosphine)carbodicarbene-rhodium complexes

Matthew J. Goldfogel, Courtney C. Roberts, Simon J. Meek

Research output: Contribution to journalArticlepeer-review

87 Scopus citations

Abstract

A carbodicarbene (CDC)-based pincer ligand scaffold is reported, along with its application to site-selective Rh(I)-catalyzed intermolecular hydroamination of 1,3-dienes with aryl and alkyl amines. To the best of our knowledge, this is the first example of the use of a well-defined CDC complex as an efficient catalyst. Transformations proceed in the presence of 1.0-5.0 mol % Rh complex at 35-120 °C; allylic amines are obtained in up to 97% yield and with >98:2 site selectivity.

Original languageEnglish (US)
Pages (from-to)6227-6230
Number of pages4
JournalJournal of the American Chemical Society
Volume136
Issue number17
DOIs
StatePublished - Apr 30 2014
Externally publishedYes

Fingerprint Dive into the research topics of 'Intermolecular hydroamination of 1,3-dienes catalyzed by bis(phosphine)carbodicarbene-rhodium complexes'. Together they form a unique fingerprint.

Cite this