Intercellular Conduits in Tumors: The New Social Network

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17 Scopus citations


The role of intercellular communication is increasingly recognized as being critical to tumoral invasion, metastasis, and development of resistance to therapy. The recent discovery of cellular protrusions – tumor microtubes – connecting cancer cells in gliomas, and tunneling nanotubes in several other forms of cancer, sheds light on a novel mechanism for molecular networking. Interrupting and disrupting vital lines of intercellular crosstalk via these membranous cellular tubes has strong potential as a novel form of cancer-directed therapy.

Original languageEnglish (US)
Pages (from-to)3-5
Number of pages3
JournalTrends in Cancer
Issue number1
StatePublished - Jan 1 2016

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.


  • brain tumor networks
  • cellular protrusions
  • glioblastoma
  • intercellular communication
  • tumor microtubes
  • tunneling nanotubes


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