Interaction of arachidonic acid and heme iron in the synthesis of prostaglandins.

Douglas A Peterson; J. M. Gerrard; G. H. Rao; E. L. Mills; J. G. White

Interaction of arachidonic acid and heme iron in the synthesis of prostaglandins.

Douglas A Peterson, J. M. Gerrard, G. H. Rao, E. L. Mills, J. G. White

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The reaction of ferrous iron and oxygen to oxidize arachidonic acid has been studied to aid in understanding the mechanism of PGG2 formation. Based on these results we have presented a novel concept of heme-arachidonic acid interaction in PG synthesis.

Original language	English (US)
Pages (from-to)	157-161
Number of pages	5
Journal	Advances in prostaglandin and thromboxane research
Volume	6
State	Published - Jan 1 1980

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@article{28228618a023421f8a901cc42208c917,

title = "Interaction of arachidonic acid and heme iron in the synthesis of prostaglandins.",

abstract = "The reaction of ferrous iron and oxygen to oxidize arachidonic acid has been studied to aid in understanding the mechanism of PGG2 formation. Based on these results we have presented a novel concept of heme-arachidonic acid interaction in PG synthesis.",

author = "Peterson, {Douglas A} and Gerrard, {J. M.} and Rao, {G. H.} and Mills, {E. L.} and White, {J. G.}",

year = "1980",

month = jan,

day = "1",

language = "English (US)",

volume = "6",

pages = "157--161",

journal = "Advances in prostaglandin and thromboxane research",

issn = "0361-5952",

publisher = "Raven Press",

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TY - JOUR

T1 - Interaction of arachidonic acid and heme iron in the synthesis of prostaglandins.

AU - Peterson, Douglas A

AU - Gerrard, J. M.

AU - Rao, G. H.

AU - Mills, E. L.

AU - White, J. G.

PY - 1980/1/1

Y1 - 1980/1/1

N2 - The reaction of ferrous iron and oxygen to oxidize arachidonic acid has been studied to aid in understanding the mechanism of PGG2 formation. Based on these results we have presented a novel concept of heme-arachidonic acid interaction in PG synthesis.

AB - The reaction of ferrous iron and oxygen to oxidize arachidonic acid has been studied to aid in understanding the mechanism of PGG2 formation. Based on these results we have presented a novel concept of heme-arachidonic acid interaction in PG synthesis.

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M3 - Article

C2 - 6770594

AN - SCOPUS:0018817074

SN - 0361-5952

VL - 6

SP - 157

EP - 161

JO - Advances in prostaglandin and thromboxane research

JF - Advances in prostaglandin and thromboxane research

ER -

Interaction of arachidonic acid and heme iron in the synthesis of prostaglandins.

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