Integration of laboratory and epidemiologic studies to evaluate genotoxic exposure in tool and die workers.

Vincent F Garry, D. R. Jacobs, R. A. Kreiger, R. L. Nelson, R. Loeppky, M. E. Harkins

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

In summary, the data presented here provides perspective on the analysis of cancer in a relatively small population of tool and die workers. Each part of the effort establishes evidence for or against the presence of a workplace carcinogenic effect. Overall, the weight of evidence leads to the hypothesis that cutting fluids are a likely candidate for observed increases in urinary system cancer and perhaps other sites. Because cutting fluids and a wide variety of metals are used together, the interaction of these entities need be considered in the overall process of carcinogenesis in the workplace.

Original languageEnglish (US)
Pages (from-to)183-193
Number of pages11
JournalProgress in Clinical and Biological Research
Volume207
StatePublished - 1986

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