Integration host factor amplifies the induction of the aceBAK operon of Escherichia coli by relieving IclR repression

Ernesto Resnik, Bin Pan, Natarajan Ramani, Martin Freundlich, David C. LaPorte

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

A binding site for integration host factor (IHF) was identified upstream of the aceBAK promoter. Under inducing conditions, IHF activates aceB::lacZ expression by opposing IclR repression. In contrast, IHF has little effect on aceB::lacZ expression under repressing conditions. The ability of IHF to relieve repression under inducing but not repressing conditions allows this protein to amplify the induction of aceBAK.

Original languageEnglish (US)
Pages (from-to)2715-2717
Number of pages3
JournalJournal of bacteriology
Volume178
Issue number9
DOIs
StatePublished - May 1996

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