Integrating phosphoproteomics into the clinical management of prostate cancer

Larry C Cheng, Victor M Tan, Shridar Ganesan, Justin M Drake

Research output: Contribution to journalArticlepeer-review


Phosphoproteomic analysis of tumor samples has the potential to uncover significant insights into kinase signaling networks present in late stage prostate cancer that are complementary to genomic and transcriptomic approaches. Phosphoproteomics could potentially aid drug development in clinical trial design as well as provide utility for oncologists in the personalized therapeutic management of individual cancers through identifying novel biomarkers and druggable targets. Rapid advancement of targeted mass spectrometry platforms is underway to integrate phosphoproteomic technology with genomic assays to soon translate this information into the cancer clinic.

Original languageEnglish (US)
Pages (from-to)9
JournalClinical and Translational Medicine
Issue number1
StatePublished - Dec 2017

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