Integrating pharmacogenetic testing via medication therapy management in an outpatient family medicine clinic

Jacob T. Brown, Danielle Macdonald, Ann Yapel, Tiana Luczak, Anna Hanson, David D. Stenehjem

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Introduction: Pharmacogenetic (PGx) implementation has lagged behind the development of drug/gene pair guidelines. Materials & methods: This was a prospective study assessing the integration of PGx through medication therapy management in an outpatient clinic. Variables collected included patient diagnosis, current medications, failed or discontinued medications, PGx results/recommendations, turnaround time and pre/post clinical ratings. Results: A total of 91 participants completed study procedures with an average enrollment of approximately one consult per week. Participants were referred for testing primarily for guidance for current and future medications. The average number of recommendations per participant was 0.93. Conclusion: Integrating PGx testing into medication therapy management is feasible with PGx results available in under a week resulting in clinical recommendations in over half of patients tested.

Original languageEnglish (US)
Pages (from-to)203-212
Number of pages10
Issue number4
StatePublished - Mar 1 2021

Bibliographical note

Funding Information:
Funding for this study was provided through the Essentia Institute for Rural Health, which received funds from the Minnesota Department of Health Office of Rural and Primary Care. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.

Publisher Copyright:
© 2021 Future Medicine Ltd.


  • medication therapy management
  • outpatient
  • pharmacogenetics

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't


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