Integrated Proteomic and Glycoproteomic Characterization of Human High-Grade Serous Ovarian Carcinoma

Clinical Proteomic Tumor Analysis Consortium

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Hu et al. provide an integrated proteomic and glycoproteomic characterization of high-grade serous ovarian carcinomas and relevant non-tumor tissues, which reveals tumor-specific glycosylation, uncovers different glycosylation associated with three tumor clusters, and identifies glycosylation enzymes correlated with glycosylation alterations.

Original languageEnglish (US)
Article number108276
JournalCell reports
Volume33
Issue number3
DOIs
StatePublished - Oct 20 2020

Bibliographical note

Funding Information:
This work was supported by the National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium (CPTAC; grants U24CA160036 and U24CA210985 ).

Keywords

  • CPTAC
  • HGSC
  • glycoproteomics
  • glycosylation
  • high-grade serous ovarian carcinoma
  • mass spectrometry
  • proteomics
  • tumor clusters

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