Integrated ATAC-seq and RNA-seq analysis identifies key regulatory elements in NK cells activated with feeder cells and IL-2

Keyphrases

• Natural Killer Cells 100%
• Interleukin-2 100%
• RNA-seq Analysis 100%
• Regulatory Elements 100%
• Feeder Cells 100%
• ATAC-seq 100%
• Transcription Factor 20%
• Ex Vivo Expansion 20%
• Super-enhancer 20%
• Clinical Application 10%
• Immune Response 10%
• Epigenetics 10%
• Transcriptome 10%
• Transcriptomics 10%
• Transcriptional Activity 10%
• Cell Cycle Progression 10%
• Cytokine Activation 10%
• Chromatin Accessibility 10%
• Binding Activity 10%
• Cell Activation 10%
• Activator protein-1 (AP-1) 10%
• Growth Behavior 10%
• Natural Killer Cell Activity 10%
• Gene Set 10%
• Transcriptionally Active 10%
• Metabolic Activity 10%
• Culture Initiation 10%
• Interferon Regulatory Factor 4 (IRF4) 10%
• T-bet 10%
• Differential Binding 10%
• Natural Killer Cell Development 10%
• Enhancer Region 10%
• Eomes 10%
• Allogeneic Immunotherapy 10%
• Changes in Gene Expression 10%

Biochemistry, Genetics and Molecular Biology

• Regulatory Element 100%
• RNA Sequencing 100%
• ATAC-Seq 100%
• Feeder Cell 100%
• Interleukin 2 100%
• Natural Killer Cell 100%
• Enhancer Region 25%
• Cytokine 25%
• Transcription Factors 16%
• Epigenetics 8%
• Gene Expression 8%
• Cell Activation 8%
• Immune Response 8%
• Transcriptomics 8%
• Binding Affinity 8%
• Cell Maturation 8%
• Cell Cycle Progression 8%
• Coculture 8%
• IRF4 8%
• Transcriptome 8%
• Chromatin Accessibility 8%

Immunology and Microbiology

• Natural Killer Cell 100%
• RNA Sequencing 100%
• Interleukin 2 100%
• Feeder Cell 100%
• Enhancer Region 25%
• Cytokine 25%
• Transcription Factors 16%
• Transcriptome 8%
• Immune Response 8%
• Cell Maturation 8%
• Gene Expression 8%
• Transcriptomics 8%
• Cell Activation 8%
• Cell Cycle Progression 8%
• Binding Affinity 8%
• Coculture 8%
• Interferon Regulatory Factor 4 8%
• Immunotherapy 8%