Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Keyphrases

• Mammalian Target of Rapamycin (mTOR) 100%
• Insulin Signaling 100%
• Protein Kinase B 100%
• Proline-rich 100%
• Akt PKB 100%
• Tuberous Sclerosis Complex 25%
• Insulin 16%
• Phosphorylation 16%
• AKT Pathway 16%
• Mammalian Target of Rapamycin Signaling Pathway 16%
• Cell Growth 8%
• Cancer Treatment 8%
• Insulin Receptor Substrate 1 (IRS1) 8%
• Insulin Sensitivity 8%
• Nutrient Deprivation 8%
• Protein Synthesis 8%
• Akt Phosphorylation 8%
• Constitutive Activation 8%
• Insulin Resistance Syndrome 8%
• Kinase Domain 8%
• Binding Partners 8%
• Serum Deprivation 8%
• Metabolic Inhibition 8%
• Target of Rapamycin Kinase 8%
• Protein Kinase Akt 8%
• Physiological Requirement 8%
• Multiple Hamartoma Syndrome 8%
• Anchoring Proteins 8%

Biochemistry, Genetics and Molecular Biology

• Insulin Signaling 100%
• Protein Kinase B 100%
• Mechanistic Target of Rapamycin 100%
• Proline 100%
• Tuberous Sclerosis 15%
• phosphorylation 15%
• Insulin 10%
• Protein Biosynthesis 5%
• Insulin Sensitivity 5%
• Metabolic Inhibition 5%
• Insulin Resistance 5%
• Insulin Receptor 5%
• Cell Growth 5%