Instructing Memory in CD8+ Thymocytes

Katherine Maude Ashby, Kristin Ann Hogquist

Research output: Contribution to journalShort survey


T cells can sometimes acquire properties of a memory cell without encountering foreign antigen. Miller et al. now show that development of such ‘memory phenotype’ (MP) CD8+ T cells starts with recognition of self-ligands in the thymus, and finishes in peripheral tissues. These cells respond rapidly during infection, and infiltrate tumors, where they express high amounts of PD-1.

Original languageEnglish (US)
Pages (from-to)556-558
Number of pages3
JournalTrends in Immunology
Issue number7
StatePublished - Jul 2020

PubMed: MeSH publication types

  • Journal Article

Fingerprint Dive into the research topics of 'Instructing Memory in CD8<sup>+</sup> Thymocytes'. Together they form a unique fingerprint.

  • Cite this