Insights into Metabolites Profiling and Pharmacological Investigation of Aconitum heterophyllum wall ex. Royle Stem through Experimental and Bioinformatics Techniques

Keyphrases

• Acetic Acid-induced Writhing Test 33%
• Acid Compounds 33%
• Aconitine 33%
• Aconitum 33%
• Aconitum Heterophyllum 33%
• Aconitum Heterophyllum Wall 100%
• ADAM10 66%
• Alkaloids 33%
• Anti-inflammatory Activity 33%
• Anti-inflammatory Effect 33%
• Anti-inflammatory Molecules 33%
• Anticancer Effect 33%
• Anticancer Potential 66%
• Antinociceptive 66%
• Binding Energy 66%
• Bioactive Metabolites 33%
• Bioinformatics Methods 100%
• Boldine 33%
• Cancer Cells 33%
• Cancer-associated Proteins 33%
• Carrageenan-induced Inflammation 33%
• Chemical Constituents 33%
• Chemotaxonomy 33%
• Chrysin 33%
• Coumarin 33%
• Cyclooxygenase-2 66%
• Dose Effect 33%
• Electrospray Ionization Mass Spectrometry 33%
• Fatty Acids 33%
• Flavonoids 33%
• Formononetin 33%
• Gas Chromatography-mass Spectrometry 33%
• GC-MS Study 33%
• H9c2 33%
• H9C2 Cell Line 33%
• Hexane Extract 33%
• Hind Paw Edema 33%
• Hordenine 33%
• IC50 Value 66%
• In Silico Modeling 33%
• In Vivo Model 33%
• Inflammation 33%
• Kauralexins 33%
• Lariciresinol 33%
• Lignans 33%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 66%
• Mass Spectra 33%
• MDCK Cells 33%
• Medicarpin 33%
• MeOH Extract 33%
• Metabolic Profiling 100%
• Methanol Extract 33%
• MOE Software 33%
• Molecular Docking Analysis 33%
• Molecular Docking Studies 66%
• Negative Ion Mode 33%
• Non-volatile 33%
• O-glucoside 33%
• Orbitrap 33%
• Organic Compounds 33%
• Pharmacology 33%
• Phenolic Compounds 33%
• Positive Control 33%
• Positive Mode 33%
• Protein-ligand 33%
• Retention Index 33%
• Shogaol 33%
• Spectrum Index 33%
• Terpenoids 33%
• Tumor Progression 33%
• Zerumbone 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Aconitine 33%
• Aconitum 100%
• Anti-Inflammatory Drug 100%
• Antinociception 33%
• Boldine 33%
• Carrageenan 33%
• Chrysin 33%
• Coumarin Derivative 33%
• Fatty Acid 33%
• Flavonoid 33%
• Formononetin 33%
• Hexane 33%
• Hordenine 33%
• IC50 66%
• Inflammation 33%
• Lignan 33%
• Malignant Neoplasm 100%
• Medicarpin 33%
• Methanol 33%
• Paw Edema 33%
• Potassium Acetate 33%
• Protein Ligand 33%
• Shogaol 33%
• Terpenoid 33%
• Tumor Growth 33%
• Zerumbone 33%