Insights from HIV-1 vaccine and passive immunization efficacy trials

Shamim Ahmed, Alon Herschhorn

Research output: Contribution to journalShort surveypeer-review


An effective HIV-1 vaccine is still not available, and most vaccine efficacy trials conducted over the years resulted in no significant overall protection. Here we highlight several insights gained from these trials as well as emerging questions that may be important for further guidance to advance current research directions.

Original languageEnglish (US)
JournalTrends in Molecular Medicine
StateAccepted/In press - 2024

Bibliographical note

Publisher Copyright:
© 2024 Elsevier Ltd


  • antibody-mediated cell cytotoxicity
  • antibody-mediated protection
  • broadly neutralizing antibodies
  • HIV-1 vaccines
  • vaccine efficacy trials

PubMed: MeSH publication types

  • Journal Article


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