Innovative technologies for the recovery of phytochemicals from Stevia rebaudiana Bertoni leaves: A review

Danijela Bursać Kovačević, Marta Maras, Francisco J. Barba, Daniel Granato, Shahin Roohinejad, Kumar Mallikarjunan, Domenico Montesano, Jose M. Lorenzo, Predrag Putnik

Research output: Contribution to journalReview articlepeer-review

91 Scopus citations


Stevia rebaudiana Bertoni has gained increased industrial and scientific interests in the last 20 years, representing a suitable nutritional alternative to sucrose and artificial sweeteners. Moreover, this plant contains polyphenols, chlorophylls, and carotenoids that may be extracted for production of nutraceuticals and functional foods. Because of nutritional and technological advantages over sucrose, innovative approaches for the extraction of highly valued compounds from Stevia leaves have been developed and optimized. In contrast to conventional alternatives, innovative extraction methods allow higher yields in a shorter time, less usage of organic solvents, and reduced energy consumption. In this paper, the use of innovative extraction techniques: MAE, UAE, HPAE, PLE, SFE, PEF, HVED, cold plasma, and RSLDE for the recovery of non-nutrients with putative health benefits from Stevia leaves is discussed.

Original languageEnglish (US)
Pages (from-to)513-521
Number of pages9
JournalFood Chemistry
StatePublished - Dec 1 2018

Bibliographical note

Funding Information:
This work was supported by a grant from the Croatian Science Foundation , Croatia: “High voltage discharges for green solvent extraction of bioactive compounds from Mediterranean herbs (IP-2016-06-1913)”. D. Granato acknowledge CNPq , Brazil for a productivity grant (process 303188/2016-2). We would like to thank Arezou Sobhani for her guidance and helpful editorial feedback.

Publisher Copyright:
© 2018 Elsevier Ltd


  • Conventional extraction
  • Functional ingredients
  • Novel extraction techniques
  • Stevia rebaudiana
  • Steviol glycosides


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