Initial recovery and rebound of type F intestinal colonization botulism after administration of investigational heptavalent botulinum antitoxin

Ryan P. Fagan, Karen P. Neil, Randy Sasich, Carolina Luquez, Hakam Asaad, Susan Maslanka, Wajahat Khalil

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Investigational heptavalent botulinum antitoxin (HBAT) is now the primary antitoxin for US noninfant botulism patients. HBAT consists of equine Fab/F(ab')2 IgG fragments, which are cleared from circulation faster than whole immunoglobulins. Rebound botulism after antitoxin administration is not previously documented but occurred in our patient 10 days after HBAT administration.

Original languageEnglish (US)
Pages (from-to)e125-e128
JournalClinical Infectious Diseases
Volume53
Issue number9
DOIs
StatePublished - Nov 1 2011

Bibliographical note

Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.

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