Keyphrases
Induced Apoptosis
100%
Small Molecules
100%
Breast Cancer Cells
100%
Sirtuin 1 (SIRT1)
100%
MDA-MB-231
100%
Sirtinol
100%
MDA-MB-231 Cells
100%
SIRT1 Inhibitor
100%
Cancer Cell Lines
50%
Medicinal Chemistry
50%
Overexpression
50%
B-cell Lymphoma 2 (Bcl-2)
50%
Acetylation
50%
Metastatic Breast Cancer
50%
Histone Deacetylases
50%
Antitumor Effect
50%
Inhibitory Effect
50%
Dose Effect
50%
Flow Cytometric Analysis
50%
IC50
50%
Apoptotic Effect
50%
Cytochrome c Release
50%
K562
50%
Apoptotic Cells
50%
Mitochondrial Membrane Potential
50%
HepG2
50%
NAD+-dependent
50%
SIRT1 Activity
50%
Release Modulation
50%
Antitumor Target
50%
Pharmacology, Toxicology and Pharmaceutical Science
Malignant Neoplasm
100%
Breast Cancer
100%
Sirtinol
100%
Pharmaceutical Chemistry
50%
Metastatic Breast Cancer
50%
Protein P53
50%
IC50
50%
Cytochrome C
50%
Histone Deacetylase
50%
Chemistry
Antitumor
100%
Apoptotic
100%
Sirtinol
100%
Chemistry
50%
Acetylation
50%
IC50
50%
Histone
50%
Membrane Potential
50%
Cytochrome C
50%
Biochemistry, Genetics and Molecular Biology
Small Molecule
100%
Sirtuin1
100%
Cancer Cell
100%
Acetylation
20%
IC50
20%
Mitochondrial Membrane Potential
20%
Percentage of Apoptotic Cells
20%
P53
20%
K562 Cells
20%
Histone Deacetylase
20%
Poly ADP Ribose Polymerase
20%
Cytochrome C
20%